Keywords
multidrug resistance
South Shetland Islands
How to Cite
Abstract
In this study, 50 bacterial isolates from pristine Antarctic soil samples from King George and Greenwich Islands (South Shetland Islands) and 25 bacterial isolates from the rhizosphere of Deschampsia antarctica Desv, were characterized for their antimicrobial activity and response to 21 antibiotics.
Antibiotic susceptibility was assayed following the disc diffusion method using different groups of antibiotics: penicillins, cephalosporins, carbapenems, aminoglycosides, quinolones, tetracycline, phenicols, macrolides, sulfonamides, and trimethoprim. Antimicrobial compounds production by the Antarctic bacterial isolates were determined using the agar diffusion method, using a set of human pathogenic bacteria.
The bacterial isolates studied showed resistance to 14 (67%) out of the 21 antibiotics tested. Three bacterial isolates (4%) were resistant to at least one antibiotic and 47 (63%) were multidrug-resistant. Additionally, 26 (35%) bacterial isolates do not show antimicrobial activity and were susceptible to all antibiotics studied. Finally, 27 (36%) bacterial isolates combining antimicrobial activity and multiple resistance to antibiotics. These bacterial isolates on average presented resistance to 10 antibiotics.
The bacterial isolates combining antimicrobial activity and multiple resistance to antibiotics are especially interesting. These two capabilities probably provide a competitive advantage to Antarctic bacteria to enable them to survive in a harsh environment. These microbial isolates are potential new sources of active compounds for the control of pathogenic microorganisms.
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Copyright (c) 2022 Nancy Cristina Calisto Ulloa, Laura Navarro, Paz Orellana, Guillermo Wiese, Claudio Gómez, Piedad Cortés-Cortés, Lorena Salazar, Ana Gutiérrez, Manuel Gidekel, Gino Corsini